AICA Ribonucleotide (AICAR) 50mg

Revo Peptide is proud to offer AICA Ribonucleotide (AICAR) as a premium-grade research compound with confirmed purity of ≥99%, manufactured via chemical synthesis and rigorously verified through HPLC and mass spectrometry analysis. This product is supplied in lyophilized form and is intended strictly for qualified laboratory and scientific research environments.

Product Overview

AICA Ribonucleotide, commonly referred to as AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), is a naturally occurring intermediate in the de novo purine biosynthesis pathway. As a cell-permeable nucleotide analogue, AICAR has become a widely studied compound in metabolic and cellular biology research. Its ability to mimic the effects of AMP on key regulatory enzymes makes it a valuable tool compound for investigators studying energy homeostasis, cellular signaling, and related biochemical pathways. Researchers at Revo Peptide can order AICAR online with confidence, knowing they are receiving a consistently manufactured, analytically verified compound.

Peptide Structure & Amino Acid Sequence

AICAR is not a classical peptide but rather a mononucleotide analogue. Its full chemical name is 5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide 5′-monophosphate. The compound features an imidazole ring system attached to a ribose sugar and a phosphate group, structurally resembling adenosine monophosphate (AMP). This structural similarity underpins its recognized role in AMPK-related research. The molecular formula is C₉H₁₄N₄O₈P, and it carries a CAS number of 2627-69-2.

Chemical & Physical Characteristics

• Appearance: White lyophilized powder
• Molecular Formula: C₉H₁₄N₄O₈P
• CAS Number: 2627-69-2
• Molecular Weight: Approximately 338.21 g/mol
• Solubility: Soluble in water or 1% acetic acid
• Source: Chemical synthesis
• Storage Temperature: Stable at room temperature for up to 90 days; for extended storage, keep frozen below -8°C

These characteristics make AICAR a highly practical compound for routine laboratory workflows, offering good aqueous solubility and manageable storage requirements compared to many other research nucleotides.

Purity & Analytical Verification (HPLC & MS)

Every batch of AICA Ribonucleotide (AICAR) supplied by Revo Peptide is independently verified to a minimum purity of ≥99% using high-performance liquid chromatography (HPLC). Mass spectrometry (MS) analysis is additionally employed to confirm molecular identity, ensuring each vial meets strict research-grade standards. Certificate of Analysis (CoA) data is available upon request, providing full traceability for each production lot. Researchers can buy AICAR online from Revo Peptide with the assurance that every vial has passed rigorous multi-step quality verification.

Quality Control & Lyophilization Integrity

AICAR is supplied in lyophilized form to maximize compound stability and shelf life. The lyophilization process removes residual moisture under controlled vacuum conditions, preserving the structural and chemical integrity of the nucleotide analogue over time. Each vial is sealed under inert atmosphere conditions and undergoes visual inspection prior to dispatch. Revo Peptide’s internal quality control protocols align with recognized laboratory standards to ensure consistent batch-to-batch reproducibility for research applications.

Safety, Handling & Laboratory Precautions

AICAR is supplied exclusively for qualified research professionals operating within appropriately equipped laboratory environments. Standard laboratory personal protective equipment (PPE) — including nitrile gloves, safety eyewear, and a laboratory coat — should be worn when handling this compound. Avoid inhalation of powder and contact with skin or mucous membranes. All handling should comply with the institution’s standard operating procedures for chemical reagents. This compound is not approved for human or animal administration and must never be used outside of a controlled research setting.

Reconstitution, Packaging & Storage

AICAR demonstrates good solubility in water or 1% acetic acid, making it compatible with standard aqueous buffer systems used in laboratory research. Researchers should prepare working solutions in accordance with their experimental protocols using appropriate laboratory-grade solvents. Once reconstituted, solutions should be aliquoted and stored under conditions appropriate to the experimental timeline. The lyophilized powder is stable at room temperature for up to 90 days; however, for any extended storage period, vials should be kept in a freezer maintained below -8°C. Protect from repeated freeze-thaw cycles to preserve analytical integrity.

Intended Research Use & Market Positioning

AICAR is a widely referenced compound in the fields of metabolic biology, cellular energy regulation, and enzyme kinetics research. It is used as a tool compound in studies examining AMPK activation pathways, glucose uptake mechanisms, lipid metabolism, and mitochondrial biogenesis at the cellular level. Revo Peptide positions this compound for sale to academic institutions, pharmaceutical research organizations, and independent laboratory researchers seeking a reliable, high-purity AICAR source. This product is not intended for diagnostic, therapeutic, or any consumptive purpose.

Ordering, Availability & Fulfillment

Revo Peptide offers AICA Ribonucleotide (AICAR) for sale online with streamlined ordering, competitive pricing, and prompt fulfillment. Bulk purchasing options are available for research groups requiring larger quantities, with tiered discounts applied automatically at checkout. Orders are processed efficiently and dispatched with appropriate cold-chain packaging to maintain compound integrity during transit. Contact the Revo Peptide team directly for institutional purchase inquiries, custom quantities, or Certificate of Analysis requests.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. AICA Ribonucleotide (AICAR) is sold by Revo Peptide strictly as a laboratory research reagent. It is the sole responsibility of the purchasing researcher or institution to ensure that all applicable local, national, and international regulations governing the acquisition, storage, and use of this compound are fully observed. Revo Peptide assumes no liability for any misuse, improper handling, or use of this product outside of its intended research context.