IGF-1 DES 1mg – 50 Vials at 30% Off

Product Overview

IGF-1 DES — formally known as Des(1-3) IGF-1 — is a naturally occurring truncated analogue of Insulin-like Growth Factor 1 (IGF-1) in which the first three N-terminal amino acids (Gly-Pro-Glu) are absent. This structural modification is well-documented in the scientific literature to significantly reduce binding affinity to IGF-binding proteins (IGFBPs), resulting in a molecularly distinct variant of considerable interest to researchers studying growth factor signaling, cellular proliferation pathways, and receptor-binding kinetics. Revo Peptide now offers this compound in a convenient 50-vial bulk configuration at 30% off the standard single-vial price — making it an ideal procurement choice for laboratories requiring sustained, high-volume research supply.

Peptide Structure & Amino Acid Sequence

IGF-1 DES is a 67-amino acid peptide defined by the following verified sequence:

H-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Asp-Ala-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-Gly-Ile-Val-Asp-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Arg-Arg-Leu-Glu-Met-Tyr-Cys-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Ala-OH

The absence of the three N-terminal residues present in full-length IGF-1 is the defining structural feature of this truncated variant. This sequence is confirmed via mass spectrometry (MS) during quality-control release testing, ensuring that each vial shipped from Revo Peptide contains the correct molecular entity.

Chemical & Physical Characteristics

• Appearance: White lyophilized powder
• Molecular Formula: C₃₃₁H₅₁₂N₈₄O₁₀₁S₇ (approximate, consistent with 67-residue chain)
• Solubility: Soluble in sterile water or 1% acetic acid
• Storage Conditions: −20°C (long-term); +4°C (short-term, up to 4 weeks)
• Form: Lyophilized (freeze-dried) for maximum stability during transit and storage

These physical properties make IGF-1 DES a stable and practical research compound when handled under appropriate laboratory conditions.

Purity & Analytical Verification (HPLC & MS)

Every batch of IGF-1 DES produced for Revo Peptide undergoes rigorous dual-method analytical verification. Reverse-phase High-Performance Liquid Chromatography (RP-HPLC) is used to confirm peptide purity at ≥98% (with select batches achieving >99%), while Electrospray Ionization Mass Spectrometry (ESI-MS) confirms molecular identity by matching the observed molecular weight against the theoretical value for the confirmed amino acid sequence. Certificates of Analysis (CoA) reflecting these results are available upon request for every lot number.

Quality Control & Lyophilization Integrity

Each vial in this 50-vial bulk pack is individually filled, lyophilized, and sealed under inert atmosphere conditions to prevent oxidation and moisture uptake. Revo Peptide’s quality-control pipeline includes in-process checks at multiple manufacturing stages — from raw amino acid sourcing through solid-phase peptide synthesis (SPPS), purification, lyophilization, and final vial inspection. Only batches meeting all release criteria proceed to packaging and fulfillment.

Safety, Handling & Laboratory Precautions

IGF-1 DES is supplied exclusively as a laboratory research reagent. Researchers handling this compound should follow standard peptide laboratory safety practices, including the use of appropriate personal protective equipment (PPE) such as gloves, lab coat, and eye protection. Avoid inhalation of the lyophilized powder. All handling should be performed in a suitable laboratory environment consistent with institutional biosafety guidelines. This compound is not approved for, nor intended for, any human or animal administration.

Reconstitution, Packaging & Storage

For in vitro research applications, IGF-1 DES powder may be reconstituted using sterile water or 1% acetic acid as appropriate for the specific assay protocol. Researchers should consult peer-reviewed literature and institutional SOPs to determine appropriate reconstitution volumes and working concentrations for their experimental design. Each vial is hermetically sealed and individually labeled with lot number and peptide identity. Upon receipt, store vials at −20°C for long-term preservation. Avoid repeated freeze-thaw cycles to maintain compound integrity.

Intended Research Use & Market Positioning

IGF-1 DES is of significant interest to research groups investigating growth factor receptor pharmacology, anabolic signaling cascades, cell proliferation assays, and IGFBP-independent IGF-1 receptor activation. Its reduced IGFBP binding affinity makes it a valuable tool compound for dissecting the contributions of IGFBP sequestration to IGF-1 bioavailability in experimental models. This 50-vial bulk configuration is specifically designed for research teams requiring consistent, uninterrupted supply — such as academic core facilities, contract research organizations (CROs), and preclinical biotech laboratories.

Ordering, Availability & Fulfillment

Order IGF-1 DES 1mg (50 Vials) online today through Revo Peptide and take advantage of the 30% bulk discount. Our streamlined checkout process supports multiple secure payment methods, and orders are fulfilled promptly with discreet, temperature-appropriate packaging. All products are dispatched from our quality-controlled fulfillment center with tracking provided at shipment. For wholesale pricing on quantities beyond 50 vials, contact the Revo Peptide team directly for a custom quote. Buy online now and lock in the best price on this high-demand research peptide.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. IGF-1 DES is sold by Revo Peptide strictly as a laboratory research reagent for use by qualified scientific professionals in appropriately licensed research settings. The purchaser assumes full responsibility for compliance with all applicable local, national, and international laws and regulations governing the acquisition, possession, and use of research peptides. Revo Peptide makes no representations regarding the safety, efficacy, or suitability of this compound for any purpose other than legitimate scientific research.